The CRONIC-PPF Faculty

	Valentina BIASIN Priv.-Doz.in, MSc PhD Testosterone as a prognostic and mechanistic driver of sex differences in progressive pulmonary fibrosis
1st Deputy Speaker, Division of Physiology and Pathophysiology Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz Phone: +43-316-385 72911, ✉ e-mail WWW: Forschungsportal Med Uni Graz ORCID: 0000-0002-6277-1463 PubMed: PubMed (nih.gov)
• Profile     • Curriculum vitae     • Publications

List of publications:

• For a full list of publications see → Fodok Med Uni Graz

10 most significant publications:

1. Biasin V, Crnkovic S, Sahu-Osen A, Birnhuber A, El Agha E, Sinn K, Klepetko W, Olschewski A, Bellusci S, Marsh LM, Kwapiszewska G: PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol, 2020; 318(4):​L684–L697.
2. Kheirollahi V, Wasnick RM, Biasin V, Vazquez-Armendariz AI, Chu X, Moiseenko A, Weiss A, Wilhelm J, Zhang JS, Kwapiszewska G, Herold S, Schermuly RT, Mari B, Li X, Seeger W, Günther A, Bellusci S, El Agha E: Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis. Nat Commun, 2019; 10(1):​2987.
3. Crnkovic S, Thekkekara Puthenparampil H, Mulch S, Biasin V, Radic N, Wilhelm J, Bartkuhn M, Bonyadi Rad E, Wawrzen A, Matzer I, Mitra A, Leib RD, Nagy BM, Sahu-Osen A, Valzano F, Bordag N, Evermann M, Hoetzenecker K, Olschewski A, Ljubojevic-Holzer S, Wygrecka M, Stenmark K, Marsh LM, de Jesus Perez V, Kwapiszewska G: Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease. eLife, 2025; 13:​RP98558.
4. Bordag N, Biasin V, Schnoegl D, Valzano F, Jandl K, Nagy BM, Sharma N, Wygrecka M, Kwapiszewska G, Marsh LM: Machine Learning Analysis of the Bleomycin Mouse Model Reveals the Compartmental and Temporal Inflammatory Pulmonary Fingerprint. iScience, 2020; 23(12):​101819.
5. Biasin V, Wygrecka M, Bärnthaler T, Jandl K, Jain PP, Bálint Z, Kovacs G, Leitinger G, Kolb-Lenz D, Kornmueller K, Peters F, Sinn K, Klepetko W, Heinemann A, Olschewski A, Becker-Pauly C, Kwapiszewska G: Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation. Thromb Haemost, 2018; 118(10):​1790–1802.
6. Bordag N, Nagy BM, Zügner E, Ludwig H, Foris V, Nagaraj C, Biasin V, Kovacs G, Kneidinger N, Bodenhofer U, Magnes C, Maron BA, Ulrich S, Lange TJ, Eichmann TO, Hoetzenecker K, Pieber T, Olschewski H, Olschewski A: Lipid Ratios for Diagnosis and Prognosis of Pulmonary Hypertension. Am J Respir Crit Care Med, 2025; 211(7):​1264–1276.
7. Biasin V, Wygrecka M, Marsh LM, Becker-Pauly C, Brcic L, Ghanim B, Klepetko W, Olschewski A, Kwapiszewska G: Meprin β contributes to collagen deposition in lung fibrosis. Sci Rep, 2017; 7:​39969.
8. Biasin V, Marsh LM, Egemnazarov B, Wilhelm J, Ghanim B, Klepetko W, Wygrecka M, Olschewski H, Eferl R, Olschewski A, Kwapiszewska G: Meprin β, a novel mediator of vascular remodelling underlying pulmonary hypertension. J Pathol, 2014; 233(1):​7–17.
9. Biasin V, Chwalek K, Wilhelm J, Best J, Marsh LM, Ghanim B, Klepetko W, Fink L, Schermuly RT, Weissmann N, Olschewski A, Kwapiszewska G: Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent. Int J Biochem Cell Biol, 2014; 54:​137–148.
10. Birnhuber A, Egemnazarov B, Biasin V, Bonyadi Rad E, Wygrecka M, Olschewski H, Kwapiszewska G, Marsh LM: CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis. Respir Res, 2020; 21(1):​167.

04.04.2026 CRONIC-PPF · Doctoral Programme “Clinical & Research Oriented Network for Innovative Classification of Progressive Pulmonary Fibrosis”