The CRONIC-PPF Faculty

	Gregor GORKIEWICZ Assoc. Prof. Dr. med. univ. (MD) Gut–lung axis metabolic signaling in development of progressive pulmonary fibrosis
Professor for Medical Microbiome Research, Vice chair of the Institute of Pathology Institute of Pathology, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz Phone: +43-316-385 71743, ✉ e-mail WWW: Forschungsportal Med Uni Graz ORCID: 0000-0003-1149-4782 PubMed: PubMed (nih.gov)
• Profile      • Curriculum vitae     • Publications

List of publications:

• For a full list of publications see → Fodok Med Uni Graz

10 most significant publications:

1. Bordag N, Jandl K, Syarif AH, Gindlhuber J, Schnoegl D, Mutgan AC, Foris V, Hoetzenecker K, Boehm PM, Breyer-Kohansal R, Zeder K, Gorkiewicz G, Polverino F, Crnkovic S, Kwapiszewska G, Marsh LM: Machine learning assisted immune profiling of COPD identifies a unique emphysema subtype independent of GOLD stage. iScience, 2025; 28(7):​112966.
2. Thapa HB, Passegger CA, Fleischhacker D, Kohl P, Chen YC, Kalawong R, Tam-Amersdorfer C, Gerstorfer MR, Strahlhofer J, Schild-Prüfert K, Zechner EL, Blesl A, Binder L, Busslinger GA, Eberl L, Gorkiewicz G, Strobl H, Högenauer C, Schild S: Enrichment of human IgA-coated bacterial vesicles in ulcerative colitis as a driver of inflammation. Nat Commun, 2025; 16(1):3995.
3. Anthofer M, Windisch M, Haller R, Ehmann S, Wrighton S, Miller M, Schernthanner L, Kufferath I, Schauer S, Jelušić B, Kienesberger S, Zechner EL, Posselt G, Vales-Gomez M, Reyburn HT, Gorkiewicz G: Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infection. Front Immunol, 2024; 15:​1282680.
4. Jandl K, Berg JL, Birnhuber A, Fliesser E, Borek I, Seeliger B, David S, Schmidt JJ, Gorkiewicz G, Zacharias M, Welte T, Olschewski H, Heinemann A, Wygrecka M, Kwapiszewska G: Basement membrane product, endostatin, as a link between inflammation, coagulation and vascular permeability in COVID-19 and non-COVID-19 acute respiratory distress syndrome. Front Immunol, 2023; 14:​1188079.
5. Pöltl L, Kitsera M, Raffl S, Schild S, Cosic A, Kienesberger S, Unterhauser K, Raber G, Lembacher-Fadum C, Breinbauer R, Gorkiewicz G, Sebastian C, Hoefler G, Zechner EL: Microbiota-derived genotoxin tilimycin generates colonic stem cell mutations. Cell Rep, 2023; 42(3):​112199.
6. Gindlhuber J, Tomin T, Wiesenhofer F, Zacharias M, Liesinger L, Demichev V, Kratochwill K, Gorkiewicz G, Schittmayer M, Birner-Gruenberger R: Proteomic profiling of end-stage COVID-19 lung biopsies. Clin Proteomics, 2022; 19(1):46.
7. Zacharias M, Kashofer K, Wurm P, Regitnig P, Schütte M, Neger M, Ehmann S, Marsh LM, Kwapiszewska G, Loibner M, Birnhuber A, Leitner E, Thüringer A, Winter E, Sauer S, Pollheimer MJ, Vagena FR, Lackner C, Jelusic B, Ogilvie L, Durdevic M, Timmermann B, Lehrach H, Zatloukal K, Gorkiewicz G: Host and microbiome features of secondary infections in lethal covid-19. iScience, 2022; 25(9):​104926.
8. Podlesny D, Durdevic M, Paramsothy S, Kaakoush NO, Högenauer C, Gorkiewicz G, Walter J, Fricke WF: Identification of clinical and ecological determinants of strain engraftment after fecal microbiota transplantation using metagenomics. Cell Rep Med, 2022; 3(8):​100711.
9. Birnhuber A, Fließer E, Gorkiewicz G, Zacharias M, Seeliger B, David S, Welte T, Schmidt J, Olschewski H, Wygrecka M, Kwapiszewska G: Between inflammation and thrombosis: endothelial cells in COVID-19. Eur Respir J, 2021; 58(3):​2100377.
10. Kump P, Wurm P, Gröchenig HP, Wenzl H, Petritsch W, Halwachs B, Wagner M, Stadlbauer V, Eherer A, Hoffmann KM, Deutschmann A, Reicht G, Reiter L, Slawitsch P, Gorkiewicz G, Högenauer C: The taxonomic composition of the donor intestinal microbiota is a major factor influencing the efficacy of faecal microbiota transplantation in therapy refractory ulcerative colitis. Aliment Pharmacol Ther, 2018; 47(1):​67–77.

03.04.2026 CRONIC-PPF · Doctoral Programme “Clinical & Research Oriented Network for Innovative Classification of Progressive Pulmonary Fibrosis”