The CRONIC-PPF Faculty

	Susanne SATTLER Ass.-Prof. Dr. rer. nat. (PhD) The role and diagnostic value of B cells and auto-antibodies in progressive pulmonary fibrosis
Associate Professor at the Otto Loewi Research Center, Division of Pharmacology, and Division of Cardiology Division of Pharmacology, Otto Loewi Research Centre, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz Phone: +43-316-385 74090, ✉ e-mail WWW: Forschungsportal Med Uni Graz ORCID: 0000-0001-9932-4109 PubMed: PubMed (nih.gov)
• Profile      • Curriculum vitae     • Publications

List of publications:

• For a full list of publications see → Fodok Med Uni Graz

10 most significant publications:

1. de Winter N, Ji J, Sintou A, Forte E, Lee M, Noseda M, Li A, Koenig AL, Lavine KJ, Hayat S, Rosenthal N, Emanueli C, Srivastava PK, Sattler S: Persistent transcriptional changes in cardiac adaptive immune cells following myocardial infarction: New evidence from the re-analysis of publicly available single cell and nuclei RNA-sequencing data sets. J Mol Cell Cardiol, 2024; 192:​48–64.
2. Patel H, Sintou A, Chowdhury RA, Rothery S, Iacob AO, Prasad S, Rainer PP, Martinón-Torres F, Sancho-Shimizu V, Shimizu C, Dummer K, Tremoulet AH, Burns JC, Sattler S, Levin M; DIAMONDS consortium: Evaluation of Autoantibody Binding to Cardiac Tissue in Multisystem Inflammatory Syndrome in Children and COVID-19 Vaccination-Induced Myocarditis. JAMA Netw Open, 2023; 6(5):​e2314291.
3. Kuppe C, Ramirez Flores RO, Li Z, Hayat S, Levinson RT, Liao X, Hannani MT, Tanevski J, Wünnemann F, Nagai JS, Halder M, Schumacher D, Menzel S, Schäfer G, Hoeft K, Cheng M, Ziegler S, Zhang X, Peisker F, Kaesler N, Saritas T, Xu Y, Kassner A, Gummert J, Morshuis M, Amrute J, Veltrop RJA, Boor P, Klingel K, Van Laake LW, Vink A, Hoogenboezem RM, Bindels EMJ, Schurgers L, Sattler S, Schapiro D, Schneider RK, Lavine K, Milting H, Costa IG, Saez-Rodriguez J, Kramann R: Spatial multi-omic map of human myocardial infarction. Nature, 2022; 608(7924):​766–777.
4. Forte E, Perkins B, Sintou A, Kalkat HS, Papanikolaou A, Jenkins C, Alsubaie M, Chowdhury RA, Duffy TM, Skelly DA, Branca J, Bellahcene M, Schneider MD, Harding SE, Furtado MB, Ng FS, Hasham MG, Rosenthal N, Sattler S: Cross-Priming Dendritic Cells Exacerbate Immunopathology After Ischemic Tissue Damage in the Heart. Circulation, 2021; 143(8):​821–836.
5. Che J, Najer A, Blakney AK, McKay PF, Bellahcene M, Winter CW, Sintou A, Tang J, Keane TJ, Schneider MD, Shattock RJ, Sattler S, Stevens MM: Neutrophils Enable Local and Non-Invasive Liposome Delivery to Inflamed Skeletal Muscle and Ischemic Heart. Adv Mater; 2020; 32(48):​e2003598.
6. Sintou A, Mansfield C, Iacob A, Chowdhury RA, Narodden S, Rothery SM, Podovei R, Sanchez-Alonso JL, Ferraro E, Swiatlowska P, Harding SE, Prasad S, Rosenthal N, Gorelik J, Sattler S: Mediastinal Lymphadenopathy, Class-Switched Auto-Antibodies and Myocardial Immune-Complexes During Heart Failure in Rodents and Humans. Front Cell Dev Biol, 2020; 8:695.
7. Baxan N, Papanikolaou A, Salles-Crawley I, Lota A, Chowdhury R, Dubois O, Branca J, Hasham MG, Rosenthal N, Prasad SK, Zhao L, Harding SE, Sattler S: Characterization of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by multiparametric quantitative cardiac magnetic resonance imaging. Dis Model Mech, 2019; 12(8):​dmm040725.
8. Panahi M, Papanikolaou A, Torabi A, Zhang JG, Khan H, Vazir A, Hasham MG, Cleland JGF, Rosenthal NA, Harding SE, Sattler S: Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition. Cardiovasc Res, 2018; 114(11):​1445–1461.
9. Hasham MG, Baxan N, Stuckey DJ, Branca J, Perkins B, Dent O, Duffy T, Hameed TS, Stella SE, Bellahcene M, Schneider MD, Harding SE, Rosenthal N, Sattler S: Systemic autoimmunity induced by the TLR7/8 agonist Resiquimod causes myocarditis and dilated cardiomyopathy in a new mouse model of autoimmune heart disease. Dis Model Mech, 2017; 10(3):​259–270.
10. Sattler S, Ling GS, Xu D, Hussaarts L, Romaine A, Zhao H, Fossati-Jimack L, Malik T, Cook HT, Botto M, Lau YL, Smits HH, Liew FY, Huang FP: IL-10-producing regulatory B cells induced by IL-33 (Breg^IL-33) effectively attenuate mucosal inflammatory responses in the gut. J Autoimmun, 2014; 50(100):​107–122.

04.04.2026 CRONIC-PPF · Doctoral Programme “Clinical & Research Oriented Network for Innovative Classification of Progressive Pulmonary Fibrosis”