The CRONIC-PPF Faculty

	Paul W. VESELY (former STURM) Mag. Dr. rer. nat. Reprogramming epithelial metabolism to restore regenerative capacity in fibrotic lungs
Senior Post-Doctoral Trainee Otto Loewi Research Center, Lung Research Group, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz Phone: +43-316-385 72958, ✉ e-mail WWW: Forschungsportal Med Uni Graz ORCID: 0000-0003-3608-1060 PubMed: PubMed (nih.gov)
• Profile      • Curriculum vitae     • Publications

List of publications:

• For a full list of publications see → Fodok Med Uni Graz

10 most significant publications:

1. Peña de la Sancha P, Wieser BI, Schauer S, Reicher H, Sattler W, Breinbauer R, Schweiger M, Lechleitner M, Frank S, Zechner R, Kratky D, Espenshade PJ, Hoefler G, Vesely PW: Lipolysis-derived fatty acids are needed for homeostatic control of sterol element-binding protein-1c driven hepatic lipogenesis. Commun Biol, 2025; 8(1):588.
2. Kanti MM, Striessnig-Bina I, Wieser BI, Schauer S, Leitinger G, Eichmann TO, Schweiger M, Winkler M, Winter E, Lana A, Kufferath I, Marsh LM, Kwapiszewska G, Zechner R, Hoefler G, Vesely PW: Adipose triglyceride lipase-mediated lipid catabolism is essential for bronchiolar regeneration. JCI Insight, 2022; 7(9):​e149438.
3. Xie H, Heier C, Kien B, Vesely PW, Tang Z, Sexl V, Schoiswohl G, Strießnig-Bina I, Hoefler G, Zechner R, Schweiger M: Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling. Biochim Biophys Acta Mol Cell Biol Lipids, 2020; 1865(9):​158737.
4. Al-Zoughbi W, Pichler M, Gorkiewicz G, Guertl-Lackner B, Haybaeck J, Jahn SW, Lackner C, Liegl-Atzwanger B, Popper H, Schauer S, Nusshold E, Kindt AS, Trajanoski Z, Speicher MR, Haemmerle G, Zimmermann R, Zechner R, Vesely PW*, Hoefler G*: Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. Oncotarget, 2016; 7(23):​33832–33840.
5. Das SK, Stadelmeyer E, Schauer S, Schwarz A, Strohmaier H, Claudel T, Zechner R, Hoefler G, Vesely PW: Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58. Int J Mol Sci, 2015; 16(4):​8555–8568.
6. Huber MD, Vesely PW, Datta K, Gerace L: Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis. J Cell Biol, 2013; 203(3):​427–436.
7. Laimer D*, Dolznig H*, Kollmann K*, Vesely PW*, Schlederer M, Merkel O, Schiefer AI, Hassler MR, Heider S, Amenitsch L, Thallinger C, Staber PB, Simonitsch-Klupp I, Artaker M, Lagger S, Turner SD, Pileri S, Piccaluga PP, Valent P, Messana K, Landra I, Weichhart T, Knapp S, Shehata M, Todaro M, Sexl V, Höfler G, Piva R, Medico E, Ruggeri BA, Cheng M, Eferl R, Egger G, Penninger JM, Jaeger U, Moriggl R, Inghirami G, Kenner L: PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas. Nat Med, 2012; 18(11):​1699–1704.
8. Tamilarasan KP, Temmel H, Das SK, Al Zoughbi W, Schauer S, Vesely PW*, Hoefler G*: Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity. Cell Death Dis, 2012; 3(7):​e354.
9. Das SK, Eder S, Schauer S, Diwoky C, Temmel H, Guertl B, Gorkiewicz G, Tamilarasan KP, Kumari P, Trauner M, Zimmermann R, Vesely P, Haemmerle G, Zechner R, Hoefler G: Adipose triglyceride lipase contributes to cancer-associated cachexia. Science, 2011; 333(6039):​233–238.
10. Staber PB*, Vesely P*, Haq N, Ott RG, Funato K, Bambach I, Fuchs C, Schauer S, Linkesch W, Hrzenjak A, Dirks WG, Sexl V, Bergler H, Kadin ME, Sternberg DW, Kenner L, Hoefler G: The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling. Blood, 2007; 110(9):​3374–3383.

05.04.2026 CRONIC-PPF · Doctoral Programme “Clinical & Research Oriented Network for Innovative Classification of Progressive Pulmonary Fibrosis”